CB1, or cannabinoid receptor type 1, is a specific type of cannabinoid receptor found primarily in the central nervous system, including the brain and spinal cord. These receptors are part of the endocannabinoid system, a complex signaling network involved in regulating various physiological processes in the body.
CB1 receptors are the primary target of tetrahydrocannabinol (THC), the psychoactive compound found in cannabis. When THC binds to CB1 receptors, it activates them, leading to a range of effects, including euphoria, altered perception, relaxation, and increased appetite.
In addition to THC, CB1 receptors also interact with endogenous cannabinoids produced by the body, such as anandamide and 2-arachidonoylglycerol (2-AG). These endocannabinoids play a role in regulating mood, memory, pain sensation, appetite, and other functions through their interaction with CB1 receptors.