Decarboxylation is a chemical process that involves removing a carboxyl group (COOH) from a molecule, typically through the application of heat. In the context of cannabis and hemp products, decarboxylation refers to the process of activating cannabinoids such as tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) to convert them into their active forms, THC (tetrahydrocannabinol) and CBD (cannabidiol), respectively.

The decarboxylation process involves applying heat to the plant material for a specific period of time, typically at temperatures ranging from 220°F to 250°F (105°C to 121°C) for about 30 to 60 minutes. This heat breaks down the carboxyl group from the cannabinoid acids, releasing carbon dioxide (CO2) and converting THCA into THC and CBDA into CBD, along with other minor cannabinoids.

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